Research and Evaluation

Home » Resources » Case Studies » Research and Evaluation

University Teaching Hospital: A cost minimization analysis of intravenous or subcutaneous trastuzumab treatment in patients with HER2-positive breast cancer in Ireland.

Leading Edge Group was asked to compare and contrast both trastuzumab SC and IV treatment pathways in two large Irish University teaching hospitals and assess which route of administration is more cost-effective and results in greater active healthcare professional (HCP) time savings.

On average, the total HCP time saved per trastuzumab SC treatment cycle relative to trastuzumab IV treatment cycle was 59.21 minutes. Time savings in favour of trastuzumab SC resulted from quicker drug reconstitution, no IV catheter installation and removal, and less HCP monitoring. Over a full treatment course of 17 cycles, average HCP time saved accumulates to 16.78 hours with a total estimated direct cost saving of €1,609.99. Loss of productivity for patients receiving trastuzumab IV (2.15 days) was greater than that of trastuzumab SC (0.60 days) for a full treatment course.

Other Case Studies

How to Get the Most from Your Digital Transformation

There is wide acknowledgement that we need to look at digitalizing the way we work…

Town of Paradise
The Paradise Way: Continuing to Improve in the Face of Adversity

In 2019, Town of Paradise engaged Leading Edge Group to provide Lean training and support…

Aerial view of Gravenhurst
The Town of Gravenhurst: A Continuous Improvement Journey

By embracing Lean principles, the Town of Gravenhurst has established a systematic approach that fosters…

Lean Transformation in the Pulp and Paper Industry

The Challenge Leading Edge Group was engaged by the client to implement a Lean Transformation…

Contact Us

Please call or email us with any queries regarding our Lean Belt training programs.

Europe - Ireland

Co. Cork,
P24 AD90

Tel: +353 (21) 4855863


North America - Canada

60 St. Clair Avenue East Suite 805,
Toronto, ON,
M4T 1N5,

Tel: +1 (416) 637 5074


Oceania - Australia

LEI Group Australia
1/76 Heller St
VIC 3055

Tel: + 61 (03) 9854 6136